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Bone marrow transplantation is a definite treatment modality for a variety of malignant and non-malignant disorders. The procedure and technique of bone marrow transplantation metamorphosed over years and at present, peripheral blood hematopoietic stem cells are being used most after in the place of bone marrow stem cells. With the recent advances in vascular access, aphaeresis and storage, the procedure has become less painful to the donor. Though the nomenclature of BMT is changing towards Hematopoietic stem cell transplantation, “ BMT”, being the earliest name still remains popular.
BMT can be of two major types. When the patient’s own stem cells are harvested and re infused after high-dose chemotherapy, it is called Autologus BMT. This procedure is done in select diseases, when the disease status is in remission. This treatment is aimed at eliminating microscopic ( or) invisible cancer cells from the body in order to keep the patient disease free for the longest time possible. This procedure involves less morbidity and cost.
When the stem cells are harvested from HLA matched donor and infused to the patient after appropriate conditions, it is called “Allogenic BMT”. This procedure may be curative in some malignant and non-malignant diseases. It requires pre-requisites to be met before the procedure can be attempted. Long-term immunosuppresion and treatment related mortality are the hurdles for cure with this procedure.
At BIACH & RI, the BMT unit functions under the guidance of renowned Medical Oncologists & Haemotologists. This 5 bedded BMT unit has the state-of-the-art facilities to minimize infections including Hepa filters, Centralized Oxygen, Central CSSD, Mechanical Ventilators and multichannel monitors.
Apart from BMT the unit has 8 beds specially allocated for patients undergoing Intensive Chemotherapy for heamatologic malignancies.
- Multiple Myeloma
- Non-Hodgkin’s lymphoma
- Hodgkin’s lymphoma
- Acute Myeloid leukemia
- High Risk Neuroblastoma
- Relapsed / Refractor Germ cell tumor
And other indications